Below are items which have been demonstrated through scientific or clinical studies to have significant positive effects on (non-alcoholic) fatty liver disease. These are provided for educational and research purposes only. As always, be mindful of any allergies you may have and consult with your physician before starting any regimen in addition to your prescribed therapy.
- Berberine
- Astralagus
- Yu Zhu (Solomon’s seal, Rhizoma; active component diosgenin)
- Fenugreek (active component diosgenin)
- Mediterranean diet items (fruits, beans (cannellini, chickpeas, fava, green, kidney and navy), almonds, coucous, lentils, pistachios, quinoa, farro, oats; cinnamon, rosemary, paprika, basil, mint leaves, olive oil, oregano, thyme, vinegar, tahini; salmon, sardines, tuna, chicken, eggs; reduce the following: beef, goat, and lamb)
References
Montemayor S, Mascaró CM, Ugarriza L, Casares M, Llompart I, Abete I, Zulet MÁ, Martínez JA, Tur JA, Bouzas C. Adherence to mediterranean diet and NAFLD in patients with metabolic syndrome: The FLIPAN study. Nutrients. 2022 Aug 3;14(15):3186.
Nie K, Gao Y, Chen S, Wang Z, Wang H, Tang Y, Su H, Lu F, Dong H, Fang K. Diosgenin attenuates non-alcoholic fatty liver disease in type 2 diabetes through regulating SIRT6-related fatty acid uptake. Phytomedicine. 2023 Mar 1;111:154661.
Wei X, Wang C, Hao S, Song H, Yang L. The therapeutic effect of berberine in the treatment of nonalcoholic fatty liver disease: a meta-analysis. Evidence-Based Complementary and Alternative Medicine. 2016 Oct;2016.
Zhai Y, Zhou W, Yan X, Qiao Y, Guan L, Zhang Z, Liu H, Jiang J, Liu J, Peng L. Astragaloside IV ameliorates diet-induced hepatic steatosis in obese mice by inhibiting intestinal FXR via intestinal flora remodeling. Phytomedicine. 2022 Dec 1;107:154444.
